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KMID : 0357920010350050440
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Korean Journal of Pathology
2001 Volume.35 No. 5 p.440 ~ p.443
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Small Cell Carcinoma of the Ovary, Hypercalcemic Type, Large Cell Variant- A Case Report -
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Lee Jong-Sil
Lee Jong-Hak
Kim Yu-Kyung
Park Sun-Hoo
Ko Gyung-Hyuck
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Abstract
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We report the clinical and pathological features, including the immunohistochemical and electron microscopic findings, of a case of hypercalcemic type, large cell variant, ovarian small cell carcinoma. A 44-year-old woman complained of abdominal pain and dysmenorrhea. A mass on the left ovary was detected by computer tomographic scan. A total hysterectomy with bilateral salpingo-oophorectomy was done. Histologically, the tumor was predominantly composed of large cells with abundant eosinophilic cytoplasm and prominent nucleoli. Mucin-containing cells and myxoid stroma were also present. Typical follicle-like spaces with lined by small, closely packed epithelial cells with scanty cytoplasm were occasionally seen. No dense core granules were identified on electron microscopic examination.
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KEYWORD
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Ovary, Carcinoma, Small cell, Hypercalcemia
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